On-site cold pack production for direct-to-patient pharmaceutical delivery

Cold packs are produced right at the fulfillment point, so direct-to-patient (DTP) pharmaceutical delivery, including GLP-1 and other cold chain therapies, never depends on a truck showing up on time.
Pack Expo logoTalk to our team
Using water cold packs for medical and pharmaceutical shipments

Too many handoffs, too much risk

DTP logistics are growing at a 17% CAGR through 2031 and faster than most packaging supply chains were built to handle.

Getting cold chain packaging to a fulfillment center is more convoluted than it needs to be — multiple manufacturing, freezing, and trucking steps before a single pack is ready to use.


The cold pack journey before it reaches the fulfillment center
Make
Pack
Truck
Freeze
Truck
Store
Use
32–53 days
Total cycle time from order to recipient
2 truck trips
One ambient, one frozen
4 handoffs
Potentially by multiple supply chain operators

More than GLP-1s need cold chain

DTP cold chain isn't a one-drug problem. A wide range of therapy categories depend on the same 2-8°C refrigerated range:

GLP-1 & diabetes injectables
Ozempic, Wegovy, Mounjaro, Zepbound, Trulicity, and insulin (Humalog, Novolog, Lantus)
Biologics & monoclonal antibodies
Humira, Enbrel, Dupixent, Remicade, Ocrevus, and similar autoimmune and inflammatory therapies
Vaccines
Most routine and specialty vaccines shipped within the standard refrigerated range
Growth & fertility hormones
Genotropin, Humatrope, Norditropin, and refrigerated fertility injectables
RELO microfactories by Relocalize

Meet RELO:
The on-site cold-pack microfactory

RELO is a dedicated, self-operating microfactory that produces frozen cold packs right at your fulfillment center. It’s designed for seamless integration with your existing packaging operations.

How does it work? It’s simple and integrated.

Our microfactory integrates directly into your packaging operations.
It delivers frozen cold packs autonomously next to your order fulfillment.

By Relocalize
Cold pack production
Palletizing
24/7 supply
Hardware monitoring & maintenance
Installation & regulatory approvals
Restocking & supplier management
By your company
Allocating space with water & power access
Picking up the pallet

Benefits of RELO cold pack system

CHEAPER
An icon for cost reduction
Lower cost, higher margin

On-site production brings down the cost of cold packs for direct-to-patient pharmaceutical delivery by cutting out freight, storage, and distributor markups entirely. Every DTP shipment ships at a lower landed cost, with stronger margins built in from the start.

EASIER
A happy face icon
Zero CapEx, zero complexity

There's no CapEx to approve, no new headcount, and nothing to retrofit. Relocalize installs, runs, and maintains the microfactory on-site, so your team keeps ordering cold packs exactly as it does today, minus the operational overhead of managing where they come from.

SMARTER
Streamlined & sustainable operations

Cold packs are built to your DTP program's actual specs, sized for your SKUs and shaped around your delivery routes, GLP-1 shipments included. The result is a tighter fulfillment line, less warehouse space tied up in packaging, and a smaller emissions footprint from long-haul freight.

FASTER
Reliable on-demand supply

Production runs autonomously, 24/7, right at your fulfillment center. For direct-to-patient pharmaceutical delivery, that means supply that never runs out, no stockout risk, and room to scale the moment order volume does.

Lab-verified cooling performance, no freeze risk

Independent thermal testing shows Relocalize water cold packs hold their protective window longer than gel before crossing the 4°C threshold. Tested over 72 hours at an A2LA-accredited lab*
Request lab report
We run customized testing for your program, with documentation ready for regulatory submissions and QMS records.
ISTA Shipping Protocols
ASTM Mechanical Testing
Climatic Chamber (2–8°C)
Dangerous Goods Qualification
*Based on third-party tests in meal kit containers, accredited to ISO/IEC 17025:2017. Results available upon request.

The cleanest cold pack is one no human ever touches

Every RELO pack is made where it ships, with no human hands and no unknown middle-mile.

Zero third-party exposure

Made on-site at your fulfillment center. It never rides an unknown truck, pallet, or storage room before reaching your packout.

Microfactory to product. Nothing in between.

100% AI and robotics production

Filling, sealing, and freezing are fully automated and sensor-monitored. No human hands touch a pack at any point.

Removes the leading contamination risk, not just reduces it.

Relocalize water cold packs, not gel, without the tradeoff

Relocalize technology produces water cold packs with the same cooling performance as gel packs, in customizable sizes built to fit your packaging needs.

The difference shows up after delivery: a water cold pack can be drained safely rather than handled as hazardous waste. A meaningfully easier disposal experience for a patient receiving medication at home, while also reducing your Extended Producer Responsibility (EPR) burden.
Learn about Water Cold Packs
Private label water cold packs

 4 steps from deployment to receiving products

No CAPEX. No maintenance. No hiring.
Relocalize supplies cold packs as a service.
We manage your cold packs so you can focus on delivering a better product experience.

Sign a supply agreement with a guaranteed order volume
Install the microfactory at your fulfillment center
Start 24/7 autonomous production
Supply cold packs on demand

See what this saves on your volume

Every DTP program's cold chain math looks different — pack size, lane length, current excursion rate.

Share your volume and a member of our team will follow up with what switching actually saves you, no generic estimate required.

We can also arrange a microfactory visit or a cold chain consultation to assess what fits your program. Talk to our team today!